Calocurb Clinical supports Healthy Weight loss and Blood Sugar Levels

Posted on December 9, 2025 by drgaryk

Are you looking for a science-backed, natural approach to managing your appetite and supporting healthy weight loss? Ortho Molecular Products’ Calocurb CLINICAL™ is a revolutionary supplement that works with your body’s natural hunger and satiety signals.

Featuring a patented ingredient derived from New Zealand bitter hops, Calocurb CLINICAL™ offers a targeted, clinically proven way to take control of cravings and feel fuller, faster.

How Calocurb CLINICAL™ Taps into Your Gut’s Power

The secret lies in its active ingredient, Amarasate , a specific extract from New Zealand bitter hops. Unlike supplements that rely on stimulants or simple fiber, Calocurb CLINICAL uses a unique, delayed-release capsule to deliver Amarasate directly to the small intestine.

Once there, it performs a critical function:

  • Activating the “Bitter Brake”: Amarasate activates specialized bitter taste receptors (TAS2Rs) located on enteroendocrine cells in the small intestine.
  • Triggering Satiety Hormones: This activation acts as a powerful “stop eating” signal, triggering the release of key satiety (fullness) hormones:
    • GLP-1 (Glucagon-like Peptide-1)
    • CCK (Cholecystokinin)
    • PYY (Peptide YY)

These hormones work together to send strong signals to your brain that you are full, significantly reducing hunger and cravings. This process is entirely natural and works within approximately one hour of taking the capsule.

Positive Clinical Studies: Evidence of Efficacy

Calocurb CLINICAL™ isn’t just theory; it’s backed by a robust body of research, including human clinical trials. The results demonstrate its powerful effects on appetite control:

  • Reduced Hunger and Cravings: Clinical studies have shown that Amarasate can:
    • Reduce overall hunger by up to 30%.
    • Reduce food cravings by up to 40%.
    • In studies on fasting, participants reported a suppression of hunger elevation by as much as 100% and a reduction in food cravings by 120% compared to placebo.
  • Lower Caloric Intake: By managing appetite, the supplement helps with portion control, leading to a measurable reduction in food consumption. Research indicates an average reduction in caloric intake by 18%.
  • Major Hormone Boost: Studies have demonstrated that Amarasate can super-stimulate the release of satiety hormones, specifically elevating GLP-1 and CCK levels to six times baseline levels—double the normal post-meal response.

How It Supports Weight Loss and Blood Sugar

For Weight Loss

The primary mechanism—enhanced satiety—is directly beneficial for long-term weight management:

  • Calorie Control: By feeling full sooner and for longer, you naturally reduce your overall calorie intake and improve adherence to a healthy diet plan.
  • Fighting “Food Noise”: Many users report that ™ helps silence the constant preoccupation with food and obsessive cravings, making it easier to make mindful, healthy choices.
  • Supporting Fasting: The reduction in hunger during fasting periods makes it an excellent support tool for those practicing intermittent fasting or time-restricted eating.
For Blood Sugar

The release of GLP-1 is a critical factor in metabolic health and blood sugar regulation:

  • Improved Glucose Response: GLP-1 is known to improve glucose homeostasis (balance) by stimulating insulin release and slowing gastric emptying.
  • Clinical Findings: A 2022 study on Amarasate demonstrated an acute improvement in post-meal glucose levels, suggesting an additional metabolic benefit beyond just appetite suppression.

In summary, Calocurb CLINICAL™ offers a sophisticated, plant-based solution that works with your body’s natural physiology, making it a compelling tool for anyone seeking a targeted and science-driven approach to weight and metabolic health.

Calocurb CLINICAL™ is a practitioner-exclusive supplement, meaning it is only available through licensed healthcare professionals to ensure it is integrated correctly into your comprehensive health strategy.

Not available online at the clinical doses.

No prescription required.

Please stop in or call 781-893-3870 x3 to order.

Call Gary 781-893-3870 x111 or Alora 781-893-3870 x149 with any questions

How to take Calocurb Clinical™

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Why You Should Consider Creatine for Mental and Physical Well-Being

Posted on October 27, 2025 by drgaryk

Creatine, a naturally occurring compound, has long been a staple in the athletic world for its ability to boost strength and performance. However, its benefits extend far beyond the gym, impacting crucial areas like methylation, brain health, and overall well-being.

What is Creatine?

Creatine is produced in your body by the liver, kidneys, and pancreas, and it can also be obtained through your diet, primarily from animal protein sources like chicken, cod, beef, and salmon. Roughly half of your body’s creatine comes from your diet, with the rest synthesized internally. Once produced, about 95% of creatine is delivered to your skeletal muscles, where it’s used as an energy source during high-intensity activities such as sprinting, powerlifting, or jumping. The remaining 5-10% goes to other tissues, including your heart and brain.

Creatine plays a crucial role in producing adenosine triphosphate (ATP), your body’s primary form of energy. During intense exercise, ATP stores are rapidly depleted. Creatine helps regenerate ATP, providing your muscles with more energy to perform at their peak for longer durations. Creatine and Methylation

Methylation is a fundamental biochemical process involved in numerous bodily functions, including DNA repair, immune function, and detoxification. Interestingly, a significant portion of your body’s methyl groups are used to produce creatine. By supplementing with creatine, you can “spare” these methyl groups, allowing them to be utilized for other vital metabolic processes. This can be particularly beneficial for individuals who are low methylators.

Benefits for Muscle Health

Creatine’s impact on muscle health is well-documented and includes:
  • Increased Muscle Mass and Strength: Creatine helps replenish ATP faster, allowing you to train harder and longer, leading to increased lean muscle mass and improved strength. Studies have shown that creatine combined with resistance training significantly increases both upper and lower body strength.
  • Enhanced Exercise Performance: It improves athletic performance, especially in short-burst, high-intensity activities like sprinting, jumping, and powerlifting.
  • Faster Recovery: Creatine aids in post-exercise recovery by reducing energy depletion and activating satellite cells in muscles, which help heal micro-tears in muscle fibers.
  • Increased Water Content in Muscle Cells: Creatine boosts water content in muscle cells, which can stimulate protein synthesis and reduce dehydration and muscle cramps.
  • Increased Anabolic Hormones: It helps increase anabolic hormones like insulin, human growth hormone (hGH), estrogen, and testosterone, which contribute to growth and tissue repair.

Benefits for Brain Health

Beyond its physical advantages, creatine is gaining recognition for its potential cognitive benefits:

  • Improved Memory and Processing Speed: By improving cellular energy availability in the brain, creatine may, recall, and processing speed, especially under cognitive stress or fatigue. A 2024 meta-analysis found significant improvements in memory and processing speed with creatine supplementation.
  • Reduced Mental Fatigue: Creatine can help reduce mental fatigue during demanding tasks.
  • Neuroprotection: It may offer neuroprotection, safeguarding nerve cells from injury or damage. Some studies are exploring its potential in cognitive conditions like dementia.
  • Mood Support: Emerging evidence suggests creatine may help improve mood and reduce symptoms of depression or anxiety.
Who Can Benefit from Creatine?

Creatine supplementation can be beneficial for various individuals, including:

  • Athletes and Active Individuals: Especially those involved in high-intensity, short-duration activities.
  • Older Adults: Creatine can help counter age-related muscle loss (sarcopenia) and preserve strength and cognition.
  • Vegetarians and Vegans: Since creatine is primarily found in animal products, supplementation can help support muscle and cognitive function in those with plant-based diets.
  • Individuals Experiencing Fatigue or Reduced Cognitive Sharpness: Creatine can enhance brain energy and cognitive resilience.
  • Individuals Under Chronic Stress or Sleep Deprivation: It may offer some protection against stress-related conditions.

Dosing and Safety

For most adults, a daily dose of 3-5 grams of creatine monohydrate (the most studied form) is sufficient. Consistency in taking creatine is more important than timing.

Creatine is one of the most researched and reliable supplements available and is generally considered safe for most people. However, it’s always recommended to talk to a healthcare provider before starting any new supplement, especially if you have pre-existing conditions like kidney disease or are taking medications that affect kidney function. It’s also important to stay well-hydrated when taking creatine.

The Bottom Line

Creatine is a versatile supplement that offers a wide array of benefits, from enhancing physical performance and muscle growth to supporting brain health and methylation support. When combined with a balanced diet, adequate hydration, consistent sleep, and a personalized training routine, creatine can be a valuable addition to your wellness journey, helping you stay stronger and sharper for longer.

Stop in to purchase or click here to order online

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Natural Help for Back-to-School Stress

Posted on August 12, 2025 by drgaryk

As summer winds down and the new school year approaches, it’s natural for both students and parents to feel a surge of stress. New routines, busy schedules, and the emotional adjustment can take a toll on everyone’s nerves and sleep. Thankfully, gentle homeopathic options like Boiron StressCalm and SleepCalm can help ease this transition.
The “back-to-school season” can bring a variety of stressors. For students, this might include anxiety about new teachers, classmates, or academic pressures. Parents often juggle increased demands on their time, schedule changes, and the emotional well-being of their children. This can lead to increased stress and disrupted sleep patterns for the whole family.

How Boiron StressCalm Can Help

StressCalm is a plant-powered homeopathic medicine designed to reduce nervous tension, fatigue, and other occasional symptoms of stress, calming both mind and body. It’s a non-drowsy option, making it suitable for daytime use when you need to stay focused and alert. StressCalm has also been verified as gluten-free through internal testing.How

Boiron SleepCalm Can Help

For those struggling with occasional restless sleep and sleeplessness due to back-to-school jitters, SleepCalm can be a great solution. This melatonin-free homeopathic medicine is powered by passionflower and other homeopathic ingredients, helping to relieve occasional sleeplessness without causing next-day grogginess. Like StressCalm, SleepCalm has also been verified as gluten-free.Gentle and Convenient Relief

Both StressCalm and SleepCalm are designed to be gentle and non-drowsy. Many Boiron products, including StressCalm and SleepCalm, are available in meltaway pellets or tablets that don’t require food or water, making them convenient for on-the-go relief. They also have no known drug interactions.

As you prepare for the new school year, consider incorporating Boiron StressCalm and SleepCalm into your family’s wellness routine. These homeopathic medicines can help foster a sense of calm and clarity, making the transition smoother and more peaceful for

Click here for free shipping on all  Boiron Products  every day!

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Your Guide to the Many Forms of Magnesium

Posted on July 16, 2025 by drgaryk

Magnesium is often called the “master mineral,” and for good reason! This unsung hero is involved in over 300 vital processes in your body, from helping your muscles move and relax and nerves fire, to keeping your heart beating steadily and your energy levels up. Think of it as a crucial helper for nearly every system.

While magnesium is abundant in foods like leafy greens, nuts, seeds, and whole grains , many of us don’t get enough through diet alone. That’s where magnesium supplements come in. But here’s the catch: not all magnesium supplements are created equal. Different forms are absorbed differently and offer unique benefits

Magnesium’s Essential Roles in Your Body:

Before diving into specific types, it’s helpful to remember magnesium’s broad impact:

  • Energy Production: It helps convert food into the energy your cells need.
  • Muscle & Nerve Function: Crucial for muscle contraction and relaxation, and for sending nerve signals.
  • Heart Health: Helps maintain a steady heartbeat and healthy blood pressure.
  • Bone Strength: Contributes to strong bones and helps regulate calcium.
  • Blood Sugar Control: Plays a role in how your body uses insulin.
  • Stress & Sleep: Helps calm the nervous system and supports restful sleep.

Meet the Magnesium Family:

The way magnesium is “packaged” (bound to other compounds) affects how well your body absorbs it and what it’s best used for.

  • Best for: Occasional constipation and bowel preparation.2 It’s also used for general magnesium replacement.
  • How it works: It draws water into your intestines, softening stool and encouraging bowel movements.
  • Good to know: Can cause digestive upset like diarrhea, especially at higher doses.
  • Magnesium Glycinate:
  • Best for: Promoting relaxation, improving sleep quality, and reducing anxiety and stress.
  • How it works: It’s highly absorbable and gentle on the stomach. The glycine component has calming effects on the nervous system, helping with GABA production and melatonin regulation.
  • Good to know: Generally well-tolerated with minimal digestive side effects.
  • Magnesium L-Threonate:
  • Best for: Brain health, memory, learning, and cognitive function.
  • How it works: Uniquely crosses the blood-brain barrier, increasing magnesium levels directly in the brain to support neural connections and reduce inflammation.
  • Good to know: A newer form with promising research, specifically designed to target brain function.
  • Magnesium Malate:
  • Best for: Energy production, reducing fatigue, and easing muscle pain, especially in conditions like fibromyalgia.
  • How it works: Combines magnesium with malic acid, which is involved in the body’s energy-generating cycle (Krebs cycle).
  • Good to know: Highly bioavailable and generally well-tolerated. Some find it energizing, so consider taking it earlier in the day.
  • Magnesium Oxide:
  • Best for: Antacid for heartburn and indigestion, or as a laxative for constipation.
  • How it works: Neutralizes stomach acid and draws water into the intestines for a laxative effect.
  • Good to know: Poorly absorbed for overall magnesium levels.  More likely to cause diarrhea.
  • Magnesium Chloride:
  • Best for: General magnesium supplementation (oral) and topical use in bath salts or oils for muscle soreness.
  • How it works: Well-absorbed orally. Topical absorption through the skin (via hair follicles) has been shown, though its systemic impact from skin application is still being researched.
  • Good to know: Can cause digestive side effects when taken orally.
  • Magnesium Sulfate (Epsom Salt):
  • Best for: Soothing aching muscles in baths.  Medically, it’s used intravenously for serious conditions like pre-eclampsia, seizures, and severe asthma attacks.
  • How it works: In baths, it’s used for muscle relaxation. Medically, it acts as a vasodilator (relaxes blood vessels) and depresses the central nervous system to prevent seizures.
  • Good to know: Oral absorption is low. Topical absorption from baths is limited for systemic benefits.
  • Magnesium Taurate:
  • Best for: Cardiovascular health, including blood pressure regulation, maintaining heart rhythm, and potentially reducing anxiety.
  • How it works: Combines magnesium with taurine, an amino acid that helps transport magnesium into cells and offers additional heart-protective and calming effects.
  • Good to know: Research is ongoing, and it should not replace prescribed treatments for heart conditions without medical guidance.
  • Magnesium Orotate:
  • Best for: Supporting heart health, including lowering blood pressure and preventing irregular heart rhythms. Also used for muscle cramps, stress, anxiety, and migraines.
  • How it works: Orotic acid helps transport magnesium directly into cells, and it has antioxidant properties.  It may improve vasodilation and have antiarrhythmic effects.
  • Good to know: Generally well-tolerated with fewer gastrointestinal side effects.
  • Magnesium Aspartate:
  • Best for: General magnesium supplementation to address deficiency, muscle cramps, stress, fatigue, and supporting cardiovascular function and sleep.
  • How it works: The aspartic acid helps enhance magnesium absorption and its uptake into cells, supporting muscle relaxation, energy production, and nerve function.
  • Good to know: Considered highly bioavailable and well-absorbed.
  • Magnesium Gluconate:
  • Best for: Preventing and treating low magnesium levels, and can help with symptoms of excess stomach acid.
  • How it works: Acts as a cofactor in many enzyme reactions and can have a laxative effect due to its osmotic activity.
  • Good to know: Can cause diarrhea.
  • Magnesium Hydroxide:
  • Best for: Treating occasional constipation and as an antacid for heartburn and upset stomach.
  • How it works: Neutralizes stomach acid and draws water into the intestines to soften stool.
  • Good to know: Primarily has local effects in the digestive tract; systemic absorption for nutritional purposes is limited.  Can cause diarrhea.
  • Magnesium Lactate:
  • Best for: Preventing and treating low magnesium levels, and supporting heart, nervous, and digestive system functions.
  • How it works: A highly bioavailable form that helps maintain normal electrical activity in cells and supports various enzymatic reactions.
  • Good to know: Generally well-tolerated, but can cause diarrhea.

Important Considerations:

  • Talk to Your Doctor: Always consult a healthcare professional before starting any new supplement, especially if you have existing health conditions (like kidney issues) or are taking medications. Magnesium can interact with certain drugs, including antibiotics, diuretics, and bisphosphonates.
  • Bioavailability Matters: The “elemental magnesium” listed on a supplement label doesn’t tell the whole story. How well your body absorbs that magnesium (its bioavailability) is key. Organic forms (like citrate, glycinate, malate) are generally better absorbed than inorganic forms (like oxide, sulfate).
  • Side Effects: While generally safe, high doses of magnesium supplements can cause digestive issues like diarrhea, nausea, and stomach cramps.

By understanding the different forms of magnesium and their unique properties, you can make more informed choices to support your health and well-being.

Stop in, call 781-893-3870 x3 or click a link to purchase.  Stop in, call or email gary@naturalcompounder.com with any questions about which magnesium supplement would be helpful for you.

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Fiber Pre by Orthomolecular: A Functional Fiber Supplement for Gut Health, Satiety and Blood Sugar Balance

Posted on May 21, 2025 by drgaryk

Fiber is one of the most underrated yet essential nutrients in a healthy diet. It supports digestion, balances blood sugar, promotes feelings of fullness, and plays a crucial role in maintaining a healthy gut microbiome. With many people falling short of daily fiber goals, supplements can help fill the gap—especially when they offer more than just roughage. Fiber Pre by Ortho Molecular is a cutting-edge fiber supplement formulated to deliver targeted support for gut health, GLP-1 activation, microbiome diversity, and blood sugar regulation—making it ideal for a wide range of health goals.

What Is Fiber and Why Does It Matter?

Fiber is a type of carbohydrate found in plant foods that the human body can’t fully digest. It comes in two main forms:

  • Soluble fiber dissolves in water, slows digestion, and helps stabilize blood sugar levels.
  • Insoluble fiber adds bulk to stool and supports regular bowel movements.
Together, these fibers contribute to:
  • Improved digestion
  • Stable blood sugar
  • Reduced appetite
  • Better gut health

Despite its benefits, most people don’t meet the recommended 25–38 grams of fiber per day, making fiber supplements a valuable tool.

Why Choose Fiber Pre by Ortho Molecular?

Fiber Proe stands out as a functional fiber supplement with 11 grams of fiber per serving—8g soluble and 3g insoluble—to support a range of metabolic and digestive needs. But it’s not just about hitting fiber targets. Fiber MGP includes clinically researched ingredients to optimize microbiome health, enhance satiety, and support GLP-1 activation, a hormone critical to appetite and glucose control.

Key Functional Ingredients in Fiber Pre

Livaux® (Gold Kiwifruit Powder)

  • Increases levels of Faecalibacterium prausnitzii, a key anti-inflammatory gut bacteria.
  • Supports butyrate production, gut lining integrity, and GLP-1 hormone activation.
  • Reduces bloating and improves stool regularity, especially in individuals with functional constipation.
Solnul® (Resistant Potato Starch)
  • Enhances gut microbiome diversity and increases Akkermansia muciniphila—a marker of metabolic and gut health—by up to 238%.
  • Promotes GLP-1 production and may reduce histamine levels by supporting histamine-degrading bacteria.
Baobab Fruit Powder
  • A rich source of fiber, polyphenols, vitamins, and minerals.
  • Promotes SCFA (short-chain fatty acid) production and beneficial shifts in microbiome composition.
  • Enhances satiety, which may assist with healthy weight management.
Top Benefits of Fiber Pre
Gut Microbiome Support

The prebiotic fibers in Fiber Pre help feed beneficial bacteria and support a healthy microbial environment, enhancing digestion, immunity, and inflammation control.

Bowel Regularity

With its balanced fiber profile, Fiber Pre helps normalize stool consistency and relieve constipation naturally.

Blood Sugar Balance

Soluble fibers and GLP-1-activating ingredients slow glucose absorption and promote stable energy levels throughout the day.

Satiety and Weight Management

Fiber slows digestion and promotes a feeling of fullness, which may help reduce snacking and support a healthy weight.

Suggested Use

Start with ½ to 1 scoop per day, mixed into water, smoothies, or your favorite shake. Adjust based on your individual fiber needs and tolerance.

Final Thoughts: Why Fiber Pre Deserves a Place in Your Routine

Fiber is far more than a digestive aid—it’s a key nutrient for metabolic, microbial, and hormonal balance. Fiber Pre goes beyond the basics, offering a clinically backed, functional fiber formula that supports gut health, blood sugar regulation, and appetite control.

If you are looking to elevate your fiber intake with a supplement that works with your body on multiple levels, Fiber Pre by Ortho Molecular is a smart, science-based solution.

Stop in or click here to order on-line.

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Spring Allergy Season is Here- Healthy Choices to help with your Allergies

Posted on April 14, 2025 by drgaryk

Spring has arrived and that means pollen is in the air.  Many people are already experiencing allergy symptoms.

Now is the time to start supporting your body to help it deal with the pollens and allergens that will be increasing each week as spring flowers and trees start blooming.

Histamine is a chemical compound that is naturally produced in the body and is involved in various physiological processes such as immune response, inflammation, and digestion.  However, when histamine levels become elevated, it can lead to a variety of health problems.

Some of the problems that high histamine can cause include:

  1. Allergic reactions: Histamine is a key mediator of allergic reactions. When the body is exposed to an allergen, such as pollen, histamine is released from mast cells and causes symptoms such as itching, hives, swelling, and difficulty breathing.
  2. Digestive issues: Histamine plays a role in regulating stomach acid production and digestion. When histamine levels are high, it can lead to an increase in stomach acid production, which can cause symptoms such as heartburn, indigestion, and reflux.
  3. Headaches and migraines: Histamine can cause the blood vessels in the brain to dilate, leading to headaches and migraines.
  4. Skin problems: High histamine levels can lead to skin problems such as itching, rashes, and flushing.
  5. Anxiety and mood disorders: Histamine can also affect the central nervous system, leading to symptoms such as anxiety, irritability, and depression.
  6. Sleep disorders: Histamine is involved in regulating the sleep-wake cycle. High levels of histamine can interfere with sleep, leading to insomnia and other sleep disorders.

Some common symptoms of high histamine levels include:

  • Itching
  • Hives
  • Flushing
  • Headaches
  • Migraines
  • Heartburn
  • Indigestion
  • Reflux
  • Anxiety
  • Depression
  • Insomnia
  • Fatigue

Here are some of our favorite products to help you with your allergies this spring.

Click here for some suggestions on dosages of many of these products.

Click here for more helpful products for allergies.

Each of us is unique and the products that will help support you during spring allergy season may be unique.  We will be happy to help you figure out what will help you with your springtime allergies.

The Allergy Experts at Johnson Compounding and Wellness

Spring allergy season is fast approaching, for all your allergy related medical needs and questions reach out to experts at Johnson Compounding and Wellness at 781-893-3870 x3 or email gary@naturalcompounder.com with any questions. We look forward to hearing from you. 

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Unlocking your Inner Ecosystem: How the Organic MetabolomicsTest can pave the way to better health

Posted on April 9, 2025 by drgaryk

In the quest for optimal health, many of us focus on diet and exercise. But what if the key to unlocking your well-being lies in understanding the intricate workings of your internal biochemistry? This is where the Organic Metabolomic Test (OMX) comes into play, offering a window into your metabolic processes and potentially revealing hidden imbalances that are hindering your health.

What is an Organic Metabolomic Test?

OMX is a comprehensive urine test that measures various organic acids, which are byproducts of metabolic processes.  These acids provide insight into a wide range of bodily functions. It helps identify bacterial and yeast overgrowth, which can contribute to digestive issues, inflammation and nutrient malabsorption. Assesses levels of neurotransmitter metabolites which can shed light on mood disorders, anxiety, and sleep disturbances.  Mitochondrial function evaluates how efficiently your cells produce energy, which is crucial for overall vitality, and can be linked to fatigue and chronic illness.  Examining markers related to detoxification pathways can reveal potential toxin accumulation and impaired detoxification capacity. OMX testing also identifies deficiencies in some vitamins and minerals essential for metabolic processes.

OMX provides a personalized approach to health, offering several key benefits: Identifying root causes instead of simply treating symptoms, the OMX helps pinpoint the underlying biochemical imbalances that may be contributing to health issues. The results of the OMX can guide healthcare practitioners in developing targeted interventions, including dietary changes, supplements, and lifestyle modifications.  OMX can detect imbalances before they manifest as a serious health problem, allowing for proactive intervention.  By identifying gut dysbiosis, OMX can help address issues like leaky gut, irritable bowel syndrome, and other imbalances.  Evaluating mitochondrial function, OMX can help identify and address factors contributing to fatigue and low energy.  The OMX can help identify and address toxin accumulation, supporting overall health and well-being.  Finding vitamin and mineral deficiencies, one can correct those deficiencies and optimize your body’s function.

It is important to work with a qualified healthcare professional who is experienced in interpreting OMX results.  They can help you understand the significance of your results and develop a personalized treatment plan to address any identified imbalances.

The Organic Metabolomic Test offers a powerful tool for understanding your unique biochemistry and unlocking the potential for better health.  By identifying and addressing underlying imbalances, you can pave the way for improved gut health, enhanced mental clarity, increased energy levels, and overall well-being.  If you’re looking to take a proactive approach to your health, consider exploring the benefits of OMX.

What areas of health can the OMX provide information about?

  • Nutritional and vitamin status
  • Level and flow of amino acid
  • Detoxification
  • Mood issues
  • Gut concerns
  • Overall well-being
  • Metabolic Processing
  • Amino Acid and Protein Metabolism
  • Microbial Metabolites

Here is a link to a YouTube video explaining the test.

Here is a link to view a sample report and order the test

For questions or more information, contact Gary by email gary@naturalcompounder.com or phone 781-893-3870 x111

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Why you should take Vitamin D3 with Vitamin K2

Posted on January 20, 2025 by drgaryk

Taking vitamin D3 with vitamin K2 is important because of how these nutrients work together to manage calcium in your body. This blog will explain why this combination is very important, and what can happen if you take calcium without enough vitamin D3 and K2.

Why Vitamin D3 and K2 Work Together:

  1. Calcium Absorption and Regulation:
    • Vitamin D3 helps your body absorb calcium from your diet. Without adequate vitamin D3, your body won’t absorb calcium efficiently, no matter how much you consume.
    • Vitamin K2, on the other hand, helps direct the calcium to the right places—mainly the bones and teeth. It activates certain proteins like osteocalcin, which helps bind calcium to the bone matrix. Additionally, K2 activates matrix Gla-protein (MGP), which helps prevent calcium from depositing in soft tissues like the arteries.
  2. Bone and Cardiovascular Health:
    • Bone Health: Vitamin D3 boosts calcium absorption, and vitamin K2 ensures it is effectively used to build and strengthen bones. Without K2, calcium may end up in the bloodstream or soft tissues rather than in the bones, leading to weaker bones and a higher risk of osteoporosis.
    • Cardiovascular Health: If you have high levels of calcium in the bloodstream and not enough K2 to direct it to the bones, it can lead to calcium buildup in blood vessels, contributing to arterial calcification and an increased risk of heart disease.

What Happens if You Take Calcium Without Enough Vitamin D3 and K2?

  1. Inefficient Calcium Absorption:
    • If you take calcium supplements without sufficient vitamin D3, your body may not absorb the calcium well. This means you could end up taking a lot of calcium but not using it effectively to support bone health.
  2. Calcium Build-Up in Soft Tissues:
    • Without vitamin K2, even if calcium is absorbed, there is a risk that it will be deposited in inappropriate places, such as your arteries or kidneys, leading to vascular calcification and potential kidney stones. This can increase the risk of cardiovascular disease.
  3. Weakened Bones:
    • In the absence of adequate vitamin D3, your body may not have enough calcium available to support bone health, even if you’re taking calcium supplements. Over time, this can contribute to bone density loss and conditions like osteopenia or osteoporosis.

Summary:

  • Vitamin D3 ensures calcium is absorbed properly, while vitamin K2 directs calcium to the bones and keeps it out of soft tissues, like arteries.
  • Taking calcium without sufficient vitamin D3 and K2 can lead to inefficient calcium use, weaker bones, and potential calcification of soft tissues, increasing the risk of cardiovascular disease and other complications.

Other effects of Vitamin D3

  • Can support the innate and adaptic immune response
  • Low D3 is associated with increased autoimmunity
  • Low D3 and increased susceptibility to infections

How to determine if you are taking the right amount of Vitamin D3?

There is a simple blood spot test (finger prick done at home, no blood draw necessary) if you can not have your Vitamin D level checked with your PCP.

Here is some information on why knowing your D3 level and maintaining the proper supplementation level is important.

Why Assess Vitamin D Levels?

Vitamin D deficiency has been linked to increased risk for many common and serious diseases, including some common cancers, diabetes, cardiovascular disease, and osteoporosis. Deficiency is also prevalent in infants who are solely breastfed and who do not receive Vitamin D supplementation. Adults of all ages who have darker skin (increased skin melanin) or who always wear sun protection or limit their outdoor activities, such as homebound elderly persons, are also prone to Vitamin D deficits.

Sunlight exposure is a natural source of Vitamin D and has been shown to prevent many chronic diseases. Low levels of Vitamin D are also linked to seasonal depression, particularly during the winter months with less sunlight exposure. Vitamin D can also be obtained through diet and supplementation, although there are few food sources (fatty fish, fish liver oil, and eggs) that contain it naturally. Fortified foods may contain synthetic forms of Vitamin D, which are less potent and have a shorter lifespan in the body.

MosaicDX’s Vitamin D Test is a dried blood spot analysis that quantitates 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 metabolites. The metabolite 25-hydroxyvitamin D is the major circulating form of Vitamin D in the body and the best indicator of a patient’s true vitamin status. The major biologic function of Vitamin D is to maintain the normal blood levels of calcium and phosphorus involved in bone mineralization. Vitamin D also influences the expression of more than 2,000 genes, including those responsible for the regulation of cellular proliferation, cell differentiation, apoptosis, and angiogenesis. The immune-modulating effects of Vitamin D are profound, as evidenced by the many conditions that are associated with Vitamin D deficiency.

For more information and to order Mosaic Vitamin D testing, click here.

Click below for more info and to order Vitamin D3

Vitamin D3 1000iu w/ K2 10 mcg per drop

Vitamin D3 5000 iu w/ K2 180 mcg

Contact Waltham’s Johnson Compounding and Wellness at 781-893-3870 for additional details

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Nattokinase NSK-SD40 for cardiovascular health

Posted on January 14, 2025 by drgaryk

Clinical studies show Nattokinase supports cardiovascular health.

NutraMedix Nattokinase NSK-SD40® is extracted from natto, a food that the Japanese have consumed for centuries.  Natto is made from boiled soybeans fermented with Bacillus Subtills var.m natto, and nattokinase is a product of the fermentation process.

In contrast to its name, nattokinase is unrelated to the known kinases and is instead a serine protease.  It has been used to support heart health in traditional Japanese health practices for centuries.

NutraMedix Nattokinase NSK-SD40®, utilizes a pure, non-GMO, nonirradiated, vitamin K2-free nattokinase from Japan Bio Science Laboratory.  According to JBSL, it was the first to isolate and market nattokinase, has patented the process to remove vitamin K2 from nattokinase for optimal cardiovascular support; and has a large body of research behing the product, generating two new clinical studies per year.

NutraMedix Nattokinase NSK-SD40® is recognized by the Japan Health and Nutrition Food Authorization and the Japan Nattokinase Association, and has been recognized as a novel food in the European Union.  To be approved by the JNKA, a nattokinase product must be produced by fermentation with Bacillus Subtilis var. natto, the dose must contain more than 2,000 FU per dose, must meet safety measures and the product ingredients must have been confirmed by JNKA’s certified labs.

NutraMedix Nattokinase NSK-SD40® is free of dairy and gluten. NutraMedix rigorously follows current good manufacturing practices, as do their suppliers, including stringent ID testing, microbial testing, and healvy-metal testing on both raw materials and after encapsulation

Cardiovascular Support

Nattokinase may help with cardiovascular support through several methods: healthy fibrinolytic activity support, healthy blood-pressure support, and healthy circulation support.

Fibrinolytic Support

Nattokinase helps support healthy fibrinolytic activity via several mechanisms. Nattokinase can hydrolyze both fibrin and plasmin, supports the conversion of endogenous pro-urokinase to urokinase, and helps maintain PAI-1 and t-PA already within normal range, all of which are foundational for healthy fibrinolytic activity.  Nattokinase may also help maintain D-dimer, fibrin, factor VII and VIII, and partial thromboplastin time already within the normal range.  Notably, nattokinase does not inhibit the formation of fibrin from fibrinogen, and therefore, does not affect the healing response.

Blood Pressure Support

Nattokinase may help with healthy blood-pressure support.  In a systematic review and meta-analysis of six randomized, controlled trials with a total of 546 participants, the researchers concluded that nattokinase showed significant support for both systolic blood pressure and diastolic blood pressure already within the normal range.

In a randomized, controlled trial, 73 participants age 20-80 were given nattokinase (2000FU/capsule) or a placebo daily for 8 week.  Compared to the pacebo group, the nattokinase group received significant support for both systolic and diastolic blood pressure already within the normal range.

In a placebo-controlled, multicenter trial, 79 North American participants were randomly assigned to 100mg NutraMedix Nattokinase NSK-SD40®  per day or a placebo, daily for 8 weeks.  Compared to the placebo group, the treatment group experienced significant support for maintaining both  systolic and diastolic blood pressure already within the normal range, through the was more pronounced in men.

Circulation Support

Nattokinase may help support and maintain healthy circulation. In a double blind, placebo-controlled crossover study, male participants were randomly assigned to a single dose of 2,000 FU of nattokinase or a placebo.  Two hours later, the participants immersed their hands for 1 minute in cold water (10 degrees C).  Compared to the placebo group, the nattokinase group experienced significant support for normalization of skin temperature and blood flow without changes in cardiac output or heart rate.

Healthy Inflammatory-Response Support

Nattokinase may help with healthy inflammatory-response support. In a study examining the effect of nattokinase on high-sensitivity C-reactive protein,, participants were given a single 2,000 FU capsule of NSK_SD nattokinase.  Measurements were taken at baseline and again at 2, 4, 8, and 24 hours.  During the study, nattokinase helped maintain hsCRP already within the normal range, with greater support for levels in the higher range of normal.

Safety and Cautions

This product contains soybeans. Nattokinase is generally well tolerated and has been used safely in amount up to 2,000 FU daily for up to 3 years.

When taken with anticoagulant or antiplatelet drugs, nattokinase may increase the risk of bleeding. Rarely, nattokinase has been associated with hemorrhage. Theoretically, nattokinase may have additive effects when taken with hypotensive drugs.

Safety is not documented in breastfeeding or pregnant women or children under age 3, due to insufficient safety research.

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Meno Relief – help for menopause symptoms

Posted on October 9, 2024 by drgaryk

Meno Relief is a specialized formula designed to address the diverse facets of menopause. At its core, it features rhapontic rhubarb root extract (ERR), a clinically researched ingredient
renowned for its therapeutic benefits. This potent botanical extract provides comprehensive relief, addressing the varied and interconnected symptoms women may encounter during
menopause. Its primary mechanism of action, acting as a selective estrogen receptor modulator, ensures thorough and safe support throughout this transformative phase.

Overview

Menopause is a natural and transformative phase in a woman’s life, typically occurring in the late 40s or early 50s. Hormonal shifts, marked by a decline in estrogen and progesterone,
lead to various common symptoms such as hot flashes, night sweats, mood swings, physical and mental fatigue, sexual frustration, and sleep disturbances. The onset of these symptoms commonly begins several years before menopause and persists for up to 5 years after, significantly affecting daily life and overall well-being.

While hormone therapy (HT) is effective for vasomotor symptoms, concerns about increased
risks limit its use. Meno Relief is a tailored, hormone-free solution for women during this transitional time. By harnessing the proven benefits of ERR, this product specifically addresses
hormone balance, maintains a normal inflammatory balance, and provides antioxidant support to help women navigate the challenges of menopause with greater ease and well-being.

Rhapontic Rhubarb Root Extract (ERR)

ERR is a phytoestrogen extract derived from the roots of rhapontic rhubarb (Rheum rhaponticum L.), also known as Siberian rhubarb and is recognized in scientific literature as
a solution for menopausal complaints. It has been used for cooking and medicine for centuries in parts of Asia and Europe.

In traditional medicine, its roots were believed to help with various health issues like digestion, heart health, and female reproductive health. Scientists have found that it contains
compounds called stilbenoids, some of which act like estrogen, a hormone important for women’s health. Specifically, ERR functions as a selective estrogen receptor modulator (SERM).

This means that it selectively targets estrogen receptor β (ERβ) in the body, without affecting estrogen receptor α (ERα). This specificity is documented in in-vitro studies and is crucial
because it allows ERR to deliver its benefits in addressing menopausal symptoms without influencing other estrogen receptors in the body. By targeting ERβ specifically, ERR can
provide relief from common menopausal symptoms such as hot flashes and mild mood disturbances while potentially avoiding unwanted side effects associated with the activation
of ERα. This targeted action helps ensure efficacy while minimizing the risk of adverse effects.

Its mechanism of action also involves modulation of neurotransmitters, stabilization
of luteinizing hormone (LH) levels, and potential antioxidant activity, contributing to its efficacy in alleviating 11 of the most prevalent menopausal symptoms as measured by changes in the Menopause Rating Scale II (MRS II), including hot flashes and mood disturbances.

Clinical trials support ERR’s safety and efficacy, with no adverse events reported over observational periods of up to two years and significant relief observed in menopausal symptoms.

In a 12-week randomized, double-blind, placebo-controlled study involving 109 perimenopausal women, ERR significantly improved various menopausal complaints such as hot flashes and inner restlessness as measured by the MRS II, compared to placebo.  Similarly, a 108-week observational study involving 80 subjects showed sustained alleviation of menopausal symptoms with ERR treatment.

An open observational study with 252 peri- and postmenopausal women over six months
demonstrated significant and sustained improvement in menopausal symptoms with ERR. Another 12-week study with 112 perimenopausal women showed significant reductions
in hot flashes and overall menopausal symptoms with ERR compared to placebo. Unlike many other natural remedies, ERR has been studied extensively at the same dose, making it
easier for doctors to recommend. Several studies suggest that the use of this ingredient is well-tolerated.

Directions

1 capsule per day or as recommended by your health care professional.

Does Not Contain Gluten, corn, yeast, artificial colors or flavors.

Cautions: Do not consume this product if you are pregnant or nursing.

These statements have not been evaluated by the Food and Drug Administration.

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Money back guarantee if you are not satisfied with your results

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